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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
28.48
Human Site:
Y405
Identified Species:
52.22
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
Y405
E
E
L
G
Q
V
K
Y
I
F
S
D
K
T
G
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
Y405
E
E
L
G
Q
V
K
Y
I
F
S
D
K
T
G
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
Y405
E
E
L
G
Q
V
K
Y
I
F
S
D
K
T
G
Dog
Lupus familis
XP_849357
1158
131123
Y405
E
E
L
G
Q
V
K
Y
I
F
S
D
K
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
M390
E
P
T
D
T
A
A
M
A
R
T
S
N
L
N
Rat
Rattus norvegicus
XP_223390
1134
128100
M380
F
I
N
W
D
L
D
M
H
Y
E
P
T
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
I185
M
Q
F
K
K
C
T
I
A
G
I
A
Y
G
H
Chicken
Gallus gallus
XP_420729
1223
137907
Y464
E
E
L
G
Q
V
K
Y
I
F
S
D
K
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
N169
H
K
A
D
N
T
V
N
K
K
K
T
T
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
E564
D
I
E
M
Y
H
E
E
S
N
T
P
A
M
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
S391
T
P
A
A
A
R
T
S
N
L
N
D
E
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
Y409
E
E
L
G
Q
V
E
Y
I
F
S
D
K
T
G
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
Y556
E
E
L
G
Q
I
E
Y
I
F
S
D
K
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
100
N.A.
6.6
0
N.A.
0
100
N.A.
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
13.3
100
N.A.
6.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
8
8
0
16
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
8
0
8
0
0
0
0
62
0
8
0
% D
% Glu:
62
54
8
0
0
0
24
8
0
0
8
0
8
0
0
% E
% Phe:
8
0
8
0
0
0
0
0
0
54
0
0
0
0
0
% F
% Gly:
0
0
0
54
0
0
0
0
0
8
0
0
0
8
62
% G
% His:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
16
0
0
0
8
0
8
54
0
8
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
39
0
8
8
8
0
54
0
0
% K
% Leu:
0
0
54
0
0
8
0
0
0
8
0
0
0
16
8
% L
% Met:
8
0
0
8
0
0
0
16
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
0
0
8
8
8
8
0
8
0
8
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
16
0
0
0
% P
% Gln:
0
8
0
0
54
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
54
8
0
0
0
% S
% Thr:
8
0
8
0
8
8
16
0
0
0
16
8
16
54
8
% T
% Val:
0
0
0
0
0
47
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
54
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _